Laboratory of Dr. Xiongbin Lu
Department of Medical and Molecular Genetics
IU Simon Comprehensive Cancer Center
Indiana University School of Medicine
Wishing you every blessing of this bountiful season
Lu lab members gathered celebrating
Thanksgiving
All members were truly thankful ,wishing healthy and safe future , filled with happiness and love always, to each other.11/21/2023
Dr. Dongqi Liu joins our lab on Nov,15th ,2023
So happy you've joined our team
Thank you Yujing
As you embark on this exciting new chapter of your career, Lu lab members express sincere gratitude for the time you spent working in the lab .
Your talent, dedication, and contributions have been truly remarkable, and you will be greatly missed.
2023 Medical and Molecular Genetics Symposium
Lu lab congratulates
Ishara Moulana and Grace Wang on fantastic poster presentation at the 2023 MMGE symposium!
it was great to see your research getting the recognition it deserves. Well done!"
Dr. Xinna Zhang Receives Grant
Dr. Xinna Zhang received a new R01 award from NCI!
This is a 5-year project entitled:
"Targeting MAL2-mediated endocytosis to enhance tumor cell antigen presentation."
Congratulations, Dr. Zhang!
Congratulations to the Awardees
Cancer Research Day
May 4,2023
Selected for Oral Presentation
Dr. Samantha Sharam- Pos-Docs
2nd Place
Translational Clinical Research
Ishara Moulana - Graduate Students
We are proud to announce ,
Haniyeh Eyvani has been pass PhD defense successfully.
Congratulations
We are admire your perseverance and hard work
Dr. Haniyeh Eyvani
Dr.Tao Yu
Four from our talented lab members attended the AACR Annual Meeting
The index of the meeting included two posters from Lu lab , presented by
Dr.Samantha Sharma and Ishara Moulana
April 14-19 Orlando, Florida 2023
Congratulations
Dr.Samantha Sharma
Dr.Yifan Sun
Ishara Moulana
Trustee Teaching Aword
Xinna Zhang, PHD
Dr. Xinna Zhang recived the 2023 Trestee Teaching Aword from IUSM.
This aword recognizes outstanding teaching and is givin based on nominations from students, postdoctoral fellows and residents, staff and faculty.
She will be celebrated at the IUSM All
School Meeting on May 2nd.
Congragulaton , Dr Zhang.
We are pleased to announce ,
Yifan Sun has been pass PhD defense successfully.
Congratulations on your outstanding achievement
Dr. Yifan Sun
Lu lab celebrat a farewell party of
Zhoulong Zhou, Yifan Sun and Haniyeh Eyvani on17th March/2023 .
Our lab members wished them all the best for the future endeavors.
The gathering took place in Guggman Haus Brewing Co.
Indianapolis,Indiana
Dr . Naresh Singh joins the lab on Dec 1st ,2022
Congratulations and welcome aboard!
There's always something to be thankful for
Lu lab members gathered celebrating
Thanksgiving
All members were truly thankful ,wishing healthy and safe future , filled with happiness and love always, to each other.11/22/2022
Congratulation to Dr. Samantha Sharma and Ishara Moulana for the poster presentation in the :
AACR SPECIAL CONFERENCE: TUMOR IMMUNOLOGY AND IMMUNOTHERAPY
October 21 - 24, 2022
Boston, Massachusetts
We wish you get many achievements in scientific life
2022 CANCER RESEARCH DAY Awardees
Proudly we congratulates our lab members on winning several awards for
Best Poster Presentation at Cancer Research Day :October 12-2022
1st Place
For Behavioral,Population Science/Epidemiology and Translation/Clinicl Research subgroup
Dr. Tao Yu - Post-Doc
1st Place
For Basic Science subgroup
Haniyeh Eyvani - Graduate student
3rd Place
For Basic Science subgroup
Ishara Moulana - Graduate student
MMGE Symposium
Congratulate for Dr. Tao Yu and Ishara Moulana
on the outstanding poster presentation in MMGE symposium
Sept 30th, 2022
Dr.Zhuolong Zhou's paper entitled
“An organoid-based screen for epigenetic inhibitors that stimulate antigen presentation and potentiate T-cell-mediated cytotoxicity” published in Nature Biomedical Engineering has been selected as first prize award of outstanding research for upcoming MMGE department annual symposium.
The MMGE dept symposium committee has been invited Dr.Xinna Zhang to give a presentation of this published work at the symposium on Sept 30th.
Congratulations!
Dr. Lei Liu joins the lab on June 1st ,2022
We are excitied to welcome Dr. Lei Lui to our lab!
Lu Lab members came together to celebrate the graduating of Haniyeh Eyvani and Yifan Sun from Indiana University School of Medicine. Our graduated lab members were honored on Friday, May 13, 2022 at the Murat Theatre at Old National Centre in downtown Indianapolis. Congratulations
Ishara Moulana, a PhD student in the Lu Lab was awardedan IUSCCC (Indiana University Simon Cancer Center) pilotgrant in the amount of $10,000 (for one year) in December 2021 for her project entitled"Arf6 Inhibition to Enhance Tumor Cell Antigen Presentation for Triple Negative Breast Cancer Therapy".Congratulations, Ishara!
The IUSCC will supportthe scientific portion of her project through the Joe Ward Fellowship funds
Dr. Samanta Sharma joins the lab on July 2021
We are excitied to welcome Dr. Samantha Sharma to our lab
Dr. Kevin Van der Jeught's Received the NCI Pathway to Independence Award (K99/R00) for his Cancer Immunotherapy projects.
Congratulations to Dr. Xiongbin Lu, who has become co-program leader of the Experimental and Developmental (EDT) research program at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center!
The TNBC ADC findings were highlighted in several news media.
In this video interview Dr. Xiongbin Lu describes the new drug he and his team have discovered to treat triple negative breast cancer. Click here to see the video.
Dr. Yujing Li and Yifan Sun's paper:
“Targeted immunotherapy for HER2-low breast cancer with 17p loss” was published in Science Translational Medicine.
Congratulations!!!
Researchers discover how breast cancer cells hide from immune attack.
Dr. Xiongbin Lu's collaboration paper with Dr. Xiaoming He
Dr. Yuanzhang Fang's paper:
“MAL2 drives immune evasion in breast cancer by suppressing
tumor antigen presentation” was selected as Cover for JCI.
It has also received a commentary and was highlighted in JCI This Month.
Congratulations to Haniyeh Eyvani for passing her qualifying exam!
Dr. Yu Tao's paper:
"Metabolic interventions: A new insight into the cancer immunotherapy" was published in Archives of Biochemistry and Biophysics.
Dr. Xiongbin Lu's collaboration paper with Dr. Anlong Xu and
Dr. Guohui Wan:
"RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer" was published in Gut.
2020 CCBB Best Presentation Award
Dr. Yuanzhang Fang
2020 CCBB Best Paper Award (1st Class)
Dr. Yujing Li
Congratulations to Yifan Sun for passing his qualifying exam!
Dr. Yuanzhang Fang's paper:
“MAL2 drives immune evasion in breast cancer by suppressing
tumor antigen presentation” was published in JCI.
Dr. Kevin Van der Jeught's Received the 2020-2021
Walter A. and Laura W. Deutsch Scholarship
The ST2 findings were highlighted in several news media.
Dr. Kevin Van der Jeught's paper:
“ST2 as checkpoint target for colorectal cancer
immunotherapy” was published in JCI Insight. This is the first cancer immunotherapy paper from the Lu laboratory.
This work identifies ST2-positive tumor
associated macrophages as a therapeutic target for immune checkpoint blockade therapy for treating colorectal cancer. It is a
collaboration between Dr. Lu and Dr. Sophie Paczesny.
Dr. Xiongbin Lu was recently awarded a new $2.28 million R01 grant from the National Cancer
Institute for his project entitled
“Nanotechnology for targeted therapy and fundamental understanding
of therapeutic resistance in triple negative breast cancer”.
March 9th, 2020
Dr. Kevin Van der Jeught has served as the IUSM Post-Doctoral Association’s Communications Chair of the Executive Council and has now been elected as President
Dr. Yujing Li has been elected as the IUSM PDA Treasurer.
Congratulations, Kevin and Yujing!
Feb 10th, 2020
Happy New Year!
Jan 25th, 2020
2020 - Year of the Rat
Congratulations Dr. Lu who was appointed as a Fellow of AIMBE!
2019
IU School of Medicine Postdoc Symposium
Congradulations to Dr. Yujing Li who has gain another award on his research during the poster presentation.
Sept 20th, 2019
Outstanding Post Doc Award 2019
Congradulations to Dr. Kevin Van der Jeught who the IU School of Medicines Postdoc Award for 2019.
Sept 23rd, 2019
IU School of Medicine
Detonating Cancer
An IU scientist devised a way to deliver drugs to the inner sanctum of breast cancer cells—and destroy them.
Sept 3rd, 2019
Congratulations – Dr. Xiongbin Lu, who has accepted an invitation to serve as a member of the Mechanisms of Cancer Therapeutics – 1 Study Section, Center for Scientific Review.
July 15th, 2019
IU Simon Cancer Center Research Day
Dr. Yujing Li - 1st place Postdoc Poster Award
Dr. Yuanzhang Fang - 3rd place Postdoc Poster Award
May 5th, 2019
![IMG_0374[1]](/____impro/1/onewebmedia/IMG_0374%5B1%5D.JPG?etag=%2215871-5d31ef3b%22&sourceContentType=image%2Fjpeg&ignoreAspectRatio&resize=1000,1333&quality=85 "IMG_0374[1]")
Inaugural MMGE Symposium
“Heterozygous Deletion of Chromosome 17p Renders Prostate Cancer Vulnerable to Inhibition of RNA Polymerase II” was featured and presented. Also congradulations to Dr. Yujing Li who won, not 1, but 2 award certificates alongside a lovely handcrafted pen set.
June 5th, 2019
Congratulations – Dr. Xiongbin Lu and Dr. Feng Guo, who received a new internal grant for $50k from CTSI for their GLUE project, “A scaffold-free, high-throughput biofabrication method for cancer immunotherapy”.
May 29th, 2019
Dr. Xiongbin Lu and Yifan Sun ran in the 43rd Indy Mini
The OneAmerica 500 Festival Mini-Marathon
Dr. Xiongbin Lu (2:12:50)
Yifan Sun (2:15:02)
May 4th, 2019
“Heterozygous Deletion of Chromosome 17p Renders Prostate Cancer Vulnerable to Inhibition of RNA Polymerase II” will be highlighted in the Spring Faculty Meeting next Tuesday, May 30.
May 30th, 2019
IU School of Medicine discovery may lead to precision-based strategy for triple negative breast cancer
March 20th, 2019
https://www.altmetric.com/details/56029771/news
IU School of Medicine discovery may lead to precision-based strategy for triple negative breast cancer
March 20th, 2019
https://www.altmetric.com/details/56029771/news
IU School of Medicine discovery may lead to precision-based strategy for triple negative breast cancer
March 20th, 2019
https://www.altmetric.com/details/56029771/news
IU School of Medicine Medical and Molecular
March 20th, 2019
https://www.altmetric.com/details/56029771/news
Happy New Year!
Feb 5th, 2019
2019 - Year of the Pig
Dr. Yang Yang joins the lab
October 8th, 2018
We are excitied to welcome Dr. Yang Yang to our lab!
Indiana University Melvin and Bren Simon Cancer Center
October 8th, 2018
Breast cancer researchers at Indiana University School of Medicine, IU Simon Cancer Center, and the new Vera Bradley Foundation Center for Breast Cancer Research at IU and officials from the Fort Wayne-based Vera Bradley Foundation take a moment to celebrate. During its recent Tickled Pink event, the Vera Bradley Foundation announced that $2.2 million was raised for research in 2018. Over the past 20 years, the foundation has given a total of $32.5 million to support breast cancer research at IU. Thank you, Vera Bradley Foundation!