Naresh Singh, Ph.D.

Postdoctoral Researcher

Department of Medical & Molecular Genetics

Indiana University School of Medicine

Dr. Naresh pursued his Ph.D. (Biological Sciences) from CSIR-Institute of Genomics and Integrative Biology, Delhi, India in 2022. He joined as a post-doctoral fellow at Indiana University School of Medicine, Indiana, USA.

During his Ph.D., he worked on respiratory diseases associated with exposure to diesel exhaust deciphering the disease phenotype associated with diesel exhaust exposure in mice model. His work on miRNA provided novel insights into mechanistic aspect of miR-212 and SIRT1 expression involved in pulmonary fibrosis associated with diesel exhaust exposure. Over his research career, his work has provided significant contributions towards scientific advancements in the field of immunology and published several peer-reviewed research and review papers in high-impact journals, including Science of The Total Environment and Immunobiology.

Currently, he is working under the guidance of Dr. Xiongbin Lu in the field of cancer immunotherapy. He has in-depth knowledge of immunology and has reciprocated these skills in translational studies for characterizing disease pathophysiological advancement. His future goal is to implement his knowledge and expertise in advancement of cancer immunotherapy and immune checkpoints.

Key publications:

- Srishti Vashisht, Naresh Singh, Akansha Sharma, Rakshak Kumar, Shailendra Nath Gaur, Naveen Arora. In silico tools to assess the potential allergenicity of shiitake mushroom (Lentinula edodes). Journal of the Science of Food and agriculture. 2022. https://doi.org/10.1002/jsfa.12199

-  Preeti Bansal, Naresh Singh, Jayadev Joshi, Naveen Arora, Shailendra Nath Gaur. Choline chloride attenuates the allergic airway disease by inhibiting the lysophosphatidylcholine induced response in mouse model. Current Research in Pharmacology and Drug Discovery, 100109. https://doi.org/10.1016/J.CRPHAR.2022.100109

-  Naresh Singh, and Naveen Arora. Diesel Exhaust Exposure in Mice Induces Pulmonary Fibrosis by TGF-β/Smad3 Signaling Pathway. Science of The Total Environment 2022:807 (February): 150623. https://doi.org/10.1016/J.SCITOTENV.2021.150623.

- Dhanapal Govindaraj, Swati Sharma, Naresh Singh, and Naveen Arora. T Cell Epitopes of Per a 10 Modulate Local-Systemic Immune Responses and Airway Inflammation by Augmenting Th1 and T Regulatory Cell Functions in Murine Model. Immunobiology 2019:224 (3): 462–69. https://doi.org/10.1016/j.imbio.2019.01.003.